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Essential oils from Syzygium aromaticum and Zingiber officinale, administered alone or in combination with benznidazole, reduce the parasite load in mice orally inoculated with Trypanosoma cruzi II.

Marcella Paula Mansano SartoHevillyn Fernanda Lucas da SilvaNilma de Souza FernandesAna Paula de AbreuGerson Zanusso JuniorMax Jean de Ornelas Toledo
Published in: BMC complementary medicine and therapies (2021)
Decreased parasite load, as detected by qPCR, was observed in all treatment groups (BZ, CEO, GEO and BZ + EOs), demonstrating benefits even in the absence of parasitological cure, thus opening perspectives for further studies.
Keyphrases
  • trypanosoma cruzi
  • type diabetes
  • combination therapy
  • skeletal muscle
  • insulin resistance
  • replacement therapy
  • wild type
  • life cycle