IDH1 and IDH2 Mutations in Colorectal Cancers.

Jialing HuangLi-Hui TsengVamsi PariniParvez M LokhandwalaAparna PallavajjalaErika RodriguezRena R XianLiam ChenChristopher D GockeJames R EshlemanMing-Tseh Lin

Published in: American journal of clinical pathology (2021)

IDH1/2 mutations in CRCs were uncommon but enriched in BRAF p.V600E-mutated CRCs and perhaps colitis-associated CRCs. Further studies on IDH1/2-mutated CRCs are needed to clarify their clinicopathologic features and implications for targeted therapy.

Keyphrases

wild type
low grade
high grade
young adults
ulcerative colitis