Toxoplasmic retinochoroiditis: The influence of age, number of retinochoroidal lesions and genetic polymorphism for IFN-γ +874 T/A as risk factors for recurrence in a survival analysis.
Ana Luisa Quintella do Couto AleixoRaquel Vasconcelos C de OliveiraMaíra Cavalcanti AlbuquerqueAna Luiza BiancardiAndré Luiz Land CuriEliezer Israel BenchimolMaria Regina Reis AmendoeiraPublished in: PloS one (2019)
The risk of ocular toxoplasmosis recurrence after an active episode increased with age and was significantly higher in individuals with primary lesions, which suggests that individuals with this characteristic and the elderly could benefit from recurrence prophylactic strategies with antimicrobials. Results suggest an association between IFN-γ gene polymorphism at position +874T/A and recurrence.