Effects of hypothermia and hypothermia combined with hypocapnia on cerebral tissue oxygenation in piglets.

Simone Katja Ringer Nicola Groes ClaussenNelly SpielmannMarkus Weiss

Published in: Paediatric anaesthesia (2020)

The hypothermia-induced reduction in oxygen delivery was compensated by lowered metabolic demand. However, hypothermia was not able to compensate for an additional reduction in oxygen delivery caused by simultaneous hypocapnia. This resulted in a PtO2 drop, which was not reflected by a downshift in rSO2 .

Keyphrases

cardiac arrest
brain injury
subarachnoid hemorrhage
high glucose
diabetic rats
oxidative stress
cerebral ischemia