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EEG - Imaging Evolution of the MV2 Subtype of Sporadic Creutzfeldt-Jakob Disease During the two-Year Course of the Disease.

Theodora AfrantouSyntila Styliani-AggelikiIoannidis PanagiotisSklaviadis TheodorosBoziki MarinaGrigoriadis Nikolaos
Published in: Clinical EEG and neuroscience (2022)
Sporadic Creutzfeldt-Jakob disease (sCJD) is a rare transmissible disease. According to molecular classification, six clinical phenotypes of sCJD have been described: MM1, MM2, MV1, MV2, VV1 and VV2. MV2 subtype comprises 9% of sCJD cases. Atypical clinical course has been reported to be the main caveat for the diagnosis of the MV2 subtype. We hereby present a rare case of MV2 subtype of sCJD, highlighting the evolution of clinical, EEG and imaging attributes over a two-year period, thus underlining the atypical course of the disease.
Keyphrases
  • rare case
  • machine learning
  • functional connectivity
  • deep learning
  • resting state
  • mass spectrometry
  • photodynamic therapy
  • early onset
  • single molecule