Treatment for moderate to severe atopic dermatitis in alpine and moderate maritime climates differentially affects helper T cells and memory B cells in children.
Jorn J HeeringaKarin Berthine FietenF M BruinsE van HoffenE F KnolS G M A PasmansMenno C van ZelmPublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2018)
Clinically successful treatment of AD induces changes in blood B- and T cell subsets reflecting reduced chronic inflammation. In addition, multidisciplinary inpatient treatment in the alpine climate specifically affects memory B cells, CD8+ T cells and Th2 cells. These cell types could represent good markers for treatment efficacy.