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Efficacy of fumagillin bicyclohexylamine on experimental corneal neovascularization in rat model.

M Fatih AşulaIsmail Umut OnurF Ulviye Yigit
Published in: International ophthalmology (2018)
Previously proved to be effective for treatment of microsporidial keratitis in humans, topical and subconjunctival concentration or dosing of fumagillin bicyclohexylamine failed to reduce corneal neovascularization induced by silver nitrate in this study. Further studies comparing different concentrations and dosing may detect inhibitory effects of fumagillin on corneal neovascularization without inducing toxicity.
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