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Testicular torsion-detorsion causes dysfunction of mitochondrial oxidative phosphorylation.

Hung-Jen ShihChao-Yuan ChangI-Tao HuangPei-Shan TsaiChia-Li HanChun-Jen Huang
Published in: Andrology (2021)
Testicular torsion-detorsion produced mitochondria injury and dysregulation of mitochondrial oxidative phosphorylation in ipsilateral twisted testes. Different protein expressions were identified in the mitochondrial oxidative phosphorylation complexes with testicular torsion-detorsion; new therapeutic targets may be identified to restore the oxidative phosphorylation function of germ cells.
Keyphrases
  • oxidative stress
  • protein kinase
  • germ cell
  • induced apoptosis
  • cell death
  • cell cycle arrest
  • signaling pathway
  • amino acid
  • protein protein