ALK-Fusion Transcripts Can Be Detected in Extracellular Vesicles (EVs) from Nonsmall Cell Lung Cancer Cell Lines and Patient Plasma: Toward EV-Based Noninvasive Testing.
Estela Sánchez-HerreroCarmen Campos-SilvaYaiza Cáceres-MartellLucía Robado de LopeSandra Sanz-MorenoRoberto Serna-BlascoAlejandro Rodríguez-FestaDunixe Ares TrottaPaloma Martín-AcostaCristina PatiñoMaría José CoronadoAlexandra BeneitezRicardo JaraNerea Lago-BaameiroTamara CaminoAlberto Cruz-BermúdezMaría PardoVíctor González-RumayorMar Vales-GomezMariano ProvencioAtocha RomeroPublished in: Clinical chemistry (2022)
ALK-fusion transcripts can be detected in EV-enriched fractions. These results set the stage for the development of EV-based noninvasive ALK testing.