Genotoxicity Assessment and Protective Effect of Anogeissus leiocarpus Roots against Cyclophosphamide-Induced DNA Damage In Vivo.

Aku Enam MottoPovi Lawson-EviAboudoulatif DialloKwashie Eklu-Gadegbeku

Published in: Journal of toxicology (2021)

This first finding reports that the extract of A. leiocarpus was neither genotoxic nor cytotoxic. However, it shows a protective effect against the genotoxicity and cytotoxicity induced by cyclophosphamide.

Keyphrases

dna damage
oxidative stress
high dose
low dose
diabetic rats
high glucose
dna repair
oxide nanoparticles
drug induced
adverse drug
endothelial cells