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Dosimetric study for breathing-induced motion effects in an abdominal pancreas phantom for carbon ion mini-beam radiotherapy.

Christina StenglIván D MuñozEric ArbesEvelyn RauthJeppe Brage ChristensenJosé VedelagoArmin RunzOliver JäkelJoao Seco
Published in: Medical physics (2024)
This study provides an initial understanding of how breathing-induced organ motion affects spatial fractionation during carbon ion irradiation, using an anthropomorphic phantom. A decrease in the PVDR was observed in the right kidney when breathing-induced motion was applied, potentially increasing the risk of damage to OARs. Therefore, further studies are needed to explore the clinical viability of mini-beam radiotherapy with carbon ions when irradiating abdominal regions.
Keyphrases
  • high glucose
  • diabetic rats
  • radiation therapy
  • early stage
  • oxidative stress
  • radiation induced
  • monte carlo
  • endothelial cells
  • high speed
  • quantum dots
  • high resolution
  • stress induced
  • water soluble