Prognostic significance of day 14 bone marrow evaluation in adults with Philadelphia chromosome-negative acute lymphoblastic leukemia.
Nicholas J ShortHagop M KantarjianKoji SasakiJorge E CortesFarhad RavandiDeborah A ThomasGuillermo Garcia-ManeroIssa KhouriPartow KebriaeiRichard E ChamplinSherry PierceGhayas C IssaMarina KonoplevaTapan M KadiaCarlos Bueso-RamosJoseph D KhouryNitin JainSusan M O'BrienElias JabbourPublished in: Cancer (2016)
An assessment of residual D14 BM blasts in patients with ALL is highly predictive of the achievement of CR with induction chemotherapy and of EFS and OS. However, the D14 BM blast assessment is less prognostic of long-term outcomes when an MRD assessment is also available. Cancer 2016;122:3812-3820. © 2016 American Cancer Society.