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Cholestane-3β,5α,6β-Triol Inhibits Acid-Sensing Ion Channels and Reduces Acidosis-Mediated Ischemic Brain Injury.

Huawei SunTao YangRoger SimonZhi-Gang XiongTiandong Leng
Published in: Stroke (2024)
Our study identifies Triol as a novel ASIC inhibitor, which may serve as a new pharmacological tool for studying ASICs and may also be developed as a potential drug for treating stroke.
Keyphrases
  • brain injury
  • cerebral ischemia
  • subarachnoid hemorrhage
  • atrial fibrillation
  • genome wide
  • emergency department
  • ischemia reperfusion injury
  • dna methylation
  • adverse drug