UBE2C promotes malignancy of cutaneous squamous cell carcinoma.

Ruiting Luo Ruimin BaiJiaqi GuoNingyi XianYan Zheng

Published in: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) (2023)

Our findings indicate UBE2C is up-regulated in cSCC and contributes to its malignant behavior. These results suggest UBE2C has the potential to serve as both a cSCC biomarker and a therapeutic target.

Keyphrases

squamous cell carcinoma
transcription factor
lymph node metastasis
locally advanced
climate change