Heart irradiation reduces microvascular density and accumulation of HSPA1 in mice.

Anna WalaszczykKatarzyna SzołtysekKarol JelonekJoanna PolańskaWolfgang DörrJulia HaagenPiotr WidłakDorota Gabrys

Published in: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] (2017)

This study shows that some changes induced by radiation in the heart tissue, such as reduction in microvessel density, increase in collagen deposition, and accumulation of HSPA1, are observed as long-term effects which might be associated with late radiation cardiotoxicity.

Keyphrases

heart failure
heat shock protein
radiation induced
atrial fibrillation
high fat diet induced
radiation therapy
type diabetes
adipose tissue
wound healing
tissue engineering