Impairment of Angiogenesis-Driven Clot Resolution Is a Key Event in the Progression to Chronic Thromboembolic Pulmonary Hypertension: Validation in a Novel Rabbit Model.
Rozenn QuarckLynn WillemsBirger TielemansLeanda StoianAlicja RoniszAllard WagenaarFrédéric PerrosGuido ClaessenAgnieszka CiarkaLaurent GodinasCatharina BelgeMarc JacqueminMarion DelcroixPublished in: Arteriosclerosis, thrombosis, and vascular biology (2023)
The key role of angiogenesis-driven clot resolution was validated in a reliable small-animal model reproducing the major pathophysiological hallmarks of CTEPH.