Development of a Core Set of Patient- and Caregiver-Reported Signs and Symptoms to Facilitate Early Recognition of Acute Chimeric Antigen Receptor T-Cell Therapy Toxicities.
Anne M SpanjaartElise R A PenningsMilan KosPim G N J MutsaersPieternella J LugtenburgTom van MeertenJaap A van DoesumMonique C MinnemaMargot JakSuzanne van DorpJoost S P VermaatMarjolein W M van der PoelMartijn G H van OijenMaria T KuipersInger S NijhofMarie José KerstenPublished in: JCO oncology practice (2022)
This study provides a core set of P/CROs that can serve as a framework for (eHealth) tools that aim to enable patients and caregivers to more effectively recognize and report signs and symptoms of acute toxicities after CAR T-cell therapy, which will enhance safe outpatient treatment monitoring.