CRABP2 regulates invasion and metastasis of breast cancer through hippo pathway dependent on ER status.
Xuefei FengMiao ZhangBo WangCan ZhouYudong MuJuan LiXiaoxu LiuYaochun WangZhangjun SongPei-Jun LiuPublished in: Journal of experimental & clinical cancer research : CR (2019)
Our findings indicate that CRABP2 can suppress invasion and metastasis of ER+ breast cancer and promote invasion and metastasis of ER- breast cancer by regulating the stability of Lats1 in vitro and in vivo, and it provides new ideas for breast cancer therapy.