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SRAssembler: Selective Recursive local Assembly of homologous genomic regions.

Thomas W McCarthyHsien-Chao ChouVolker P Brendel
Published in: BMC bioinformatics (2019)
SRAssembler offers an efficient tool to complement whole genome assembly software. It can be used to solve gene-specific research questions based on large genomic read samples from multiple sources and would be an expedient choice when whole genome assembly from the reads is either not feasible, too costly, or unnecessary. The program can also aid decision making on the depth of sequencing in an ongoing novel genome sequencing project or with respect to ultimate whole genome assembly strategies.
Keyphrases
  • decision making
  • copy number
  • quality improvement
  • single cell
  • genome wide
  • dna damage
  • optical coherence tomography
  • drinking water
  • single molecule
  • data analysis