Characteristics and outcomes of patients with acute myeloid leukemia admitted to intensive care unit with acute respiratory failure: a post-hoc analysis of a prospective multicenter study.
Carolina SecretoDara CheanAndry van de LouwAchille KouatchetPhilippe BauerMarco CerranoEtienne LenglinéColombe SaillardLaurent Chow-ChineAnders PernerPeter PickkersMarcio SoaresJordi RelloFrédéric PèneVirginie LemialeMichael DarmonSofiane FodilIgnacio Martin-LoechesSangeeta MehtaPeter SchellongowskiElie AzoulayDjamel MokartPublished in: Annals of intensive care (2023)
Among AML patients with ARF, factors associated with a worse outcome are related to patient's background (performance status, leukemic pulmonary involvement), symptoms, radiological findings, the need for vasopressors and the liver SOFA score. We identified three specific ARF syndromes in AML patients, which showed a prognostic significance and could guide clinicians to optimize management strategies.
Keyphrases
- acute myeloid leukemia
- respiratory failure
- intensive care unit
- mechanical ventilation
- allogeneic hematopoietic stem cell transplantation
- end stage renal disease
- extracorporeal membrane oxygenation
- ejection fraction
- chronic kidney disease
- newly diagnosed
- pulmonary hypertension
- liver failure
- prognostic factors
- case report
- drug induced
- acute respiratory distress syndrome
- patient reported outcomes
- metabolic syndrome
- depressive symptoms
- patient reported
- insulin resistance
- weight loss