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Associations of renin-angiotensin system inhibitor use with brain insulin signaling and neuropathology.

Han TongAna W CapuanoRupal I MehtaAjay SoodDavid A BennettRexford S AhimaSteven E ArnoldZoe Arvanitakis
Published in: Annals of clinical and translational neurology (2024)
Late-life RAS inhibitor use may be associated with lower brain AKT1 phosphorylation and fewer neurofibrillary tangles.
Keyphrases
  • resting state
  • white matter
  • type diabetes
  • functional connectivity
  • signaling pathway
  • cerebral ischemia
  • cell proliferation
  • multiple sclerosis
  • adipose tissue
  • blood brain barrier
  • insulin resistance
  • weight loss