Osmotically Induced Membrane Fission in Giant Polymer Vesicles: Multilamellarity and Effect of the Amphiphilic Block Lengths.

Amphiphilic block co-polymers are used to form large spherical vesicles. A sudden change in the osmotic pressure across the polymer membrane is used to induce the fission of the polymer vesicle. The membrane area to volume ratio, as expected, is observed to be a parameter suitable to describe the process and even mark the critical points along this transition. The effect of the length of the hydrophobic and hydrophilic chains on the fission process is analyzed. The effects of membrane lamellarity and initial polydispersity are thoroughly analyzed from the experimental data following mathematical models, and the phenomenon of fission in these polymer vesicles is understood via measurements characterizing the membrane, i.e., area stretch modulus.