Outcomes in Patients with Minor Stroke: Diagnosis and Management in the Post-thrombectomy Era.
Elisabeth Breese MarshSophia GirgentiEdward J LlinasAutumn O BrunsonPublished in: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics (2023)
In the era of mechanical thrombectomy and better preventative strategies, a higher number of patients are being discharged home from the hospital with the so-called minor strokes. This has significantly changed the landscape of stroke recovery. Unfortunately, while symptoms may be categorized as mild compared to individuals with higher NIH Stroke Scale scores, the physical, cognitive, and emotional sequelae can be disabling and result in failure to return to work and poor quality of life in a population with significant potential to recover fully. In this review, we discuss the current state of minor stroke, the most common pattern of resulting deficits, what is known about the underlying pathophysiology that leads to a relatively global pattern of impaired cognition following an infarct in any location, and special considerations for treatment based on this population's unique needs. Raising awareness of the current morbidity associated with minor stroke, the need for a uniform definition that allows for comparisons of individuals across studies, and further research focused on this population to optimize outcomes, has the potential to significantly improve recovery.
Keyphrases
- atrial fibrillation
- healthcare
- end stage renal disease
- mental health
- newly diagnosed
- cerebral ischemia
- chronic kidney disease
- heart failure
- prognostic factors
- physical activity
- depressive symptoms
- single cell
- metabolic syndrome
- peritoneal dialysis
- risk assessment
- insulin resistance
- multiple sclerosis
- climate change
- weight loss