Enhanced Anti-cancer Potency Using a Combination of Oleanolic Acid and Maslinic Acid to Control Treatment Resistance in Breast Cancer.

Cigir Biray AvcıFatma SogutluNeslihan Pinar OzatesBehrouz ShademanCumhur Gunduz

Published in: Advanced pharmaceutical bulletin (2022)

The results showed that the combination of these two substances showed the highest synergistic effect at the lowest dose and using MA-OA caused cancer cells to undergo apoptosis. The use of combination drugs may reduce the resistance of cancer cells to treatment.

Keyphrases

oxidative stress
endoplasmic reticulum stress
cell death
young adults
signaling pathway
smoking cessation