Comparison of different transient gene expression systems for the production of a new humanized anti-HER2 monoclonal antibody (Hersintuzumab).
Ali RoshaniMehdi MohammadiTannaz BahadoriHengameh Ahmadi ZareMohammad Ali JudakiMaryam MobiniForough Golsaz-ShiraziMahmood Jeddi-TehraniMohammad Mehdi AmiriFazel ShokriPublished in: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences (2023)
Our research shows that using Pmax and DG-44 cells in the TGE system is a cost-effective and efficient way to produce humanized monoclonal antibodies. We discovered that this method outperforms the ExpiCHO-S kit.