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Lower Fasted-State but Greater Increase in Muscle Protein Synthesis in Response to Elevated Plasma Amino Acids in Obesity.

Lee TranKaton A KrasNyssa HoffmanJayachandran RavichandranJared M DickinsonAndrew D'LugosChad C CarrollShivam H PatelLawrence J MandarinoLori RoustChristos S Katsanos
Published in: Obesity (Silver Spring, Md.) (2018)
Adults with obesity have reduced muscle protein synthesis in the fasted state, but this response is compensated for by a greater change in overall muscle protein synthesis during amino acid infusion.
Keyphrases
  • amino acid
  • skeletal muscle
  • insulin resistance
  • metabolic syndrome
  • weight loss
  • type diabetes
  • weight gain
  • high fat diet induced
  • low dose
  • adipose tissue
  • physical activity