Axially Ligated Mesohemins as Bio-Mimicking Catalysts for Atom Transfer Radical Polymerization.
Liye FuAntonina SimakovaSangwoo ParkYi WangMarco FantinKrzysztof MatyjaszewskiPublished in: Molecules (Basel, Switzerland) (2019)
Copper is the most common metal catalyst used in atom transfer radical polymerization (ATRP), but iron is an excellent alternative due to its natural abundance and low toxicity compared to copper. In this work, two new iron-porphyrin-based catalysts inspired by naturally occurring proteins, such as horseradish peroxidase, hemoglobin, and cytochrome P450, were synthesized and tested for ATRP. Natural protein structures were mimicked by attaching imidazole or thioether groups to the porphyrin, leading to increased rates of polymerization, as well as providing polymers with low dispersity, even in the presence of ppm amounts of catalysts.
Keyphrases
- metal organic framework
- electron transfer
- highly efficient
- oxide nanoparticles
- photodynamic therapy
- transition metal
- molecular dynamics
- oxidative stress
- iron deficiency
- hydrogen peroxide
- room temperature
- energy transfer
- nitric oxide
- mass spectrometry
- ionic liquid
- gold nanoparticles
- red blood cell
- small molecule
- carbon dioxide