Beneficial effects of advanced chelate technology-based 7-minerals in aflatoxin-B1 challenged broilers: toxin residue reduction, serum biochemical improvement and modulation of the mRNA expression of NF-kB and Nrf2, and genes within their pathways.
Zeynab MohammadiKamran TaherpourHossein Ali GhasemiSaideh FakharzadehZahra NoorehSomayeh KalanakyPublished in: Journal of the science of food and agriculture (2024)
In conclusion, completely replacing ITM with ACTM can benefit the metabolism and mitigate AFB1-induced immunotoxicity and oxidative damage in chickens by altering the mRNA expression of nuclear factor-kappa B and nuclear factor erythroid 2-related factor 2, and some genes downstream their signaling pathways. © 2024 Society of Chemical Industry.
Keyphrases
- nuclear factor
- toll like receptor
- genome wide
- signaling pathway
- heat stress
- bioinformatics analysis
- oxidative stress
- escherichia coli
- genome wide identification
- diabetic rats
- high glucose
- genome wide analysis
- inflammatory response
- immune response
- dna methylation
- endothelial cells
- gene expression
- transcription factor