Intrathecal dose intensification by CNS status at diagnosis in the treatment of children with acute lymphoblastic leukemia.

Omima MustafaNaglla ElimamKhalid AbdallaAeshah A AlAzmiAmal AlgamalSami Felimban

Published in: Hematology (Amsterdam, Netherlands) (2019)

ITM intensification during induction was associated with elimination of CNS recurrence in patients with CNS2 disease and childhood ALL. Controlled studies are needed to confirm this observation.

Keyphrases

acute lymphoblastic leukemia
blood brain barrier
young adults
early life
acute myeloid leukemia