Circulation of an Artemisinin-Resistant Malaria Lineage in a Traveler Returning from East Africa to France.

Romain CoppéeJustine BaillyVéronique SarrasinBertin VianouBoris Enock ZinsouEdith MazarsHugues GeorgesSamia HamaneRose Anne LavergneEric DannaouiBetty BalikagalaNaoyuki FukudaEmmanuel I Odongo-AginyaToshihiro MitaSandrine HouzéJérôme Clain

Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)

A returned traveler to Uganda presented with a Plasmodium falciparum kelch13 A675V mutant infection that exhibited delayed clearance under artesunate therapy. Parasites were genetically related to recently reported Ugandan artemisinin-resistant A675V parasites. Adequate malaria prevention measures and clinical and genotypic surveillance are important tools to avoid and track artemisinin resistance.

Keyphrases

plasmodium falciparum
public health
single cell
mesenchymal stem cells
wild type
cell therapy
smoking cessation