Neurovascular control during exercise in acute coronary syndrome patients with Gln27Glu polymorphism of β2-adrenergic receptor.

Larissa Ferreira-SantosDaniel G MartinezJosé Carlos NicolauHumberto G MoreiraMaria Janieire AlvesAlexandre C PereiraIvani C TrombettaCarlos Eduardo NegrãoMaria Urbana P B Rondon

Published in: PloS one (2017)

The exaggerated MSNA and mean BP responses during exercise suggest an increased cardiovascular risk in patients with ACS and Gln27Gln polymorphism. Exercise training emerges as an important strategy for restoring this reflex control. Gln27Glu polymorphism of ADRB2 influences exercise-induced vascular adaptation in patients with ACS.

Keyphrases

acute coronary syndrome
percutaneous coronary intervention
antiplatelet therapy
high intensity
physical activity
skeletal muscle
resistance training