Radiosensitizing effect of galunisertib, a TGF-ß receptor I inhibitor, on head and neck squamous cell carcinoma in vitro.
Bernhard J JankTeresa LenzMarkus HaasLorenz Kadletz-WankeNicholas J CampionJulia SchnoellGregor HeiduschkaKarin MacfeldaPublished in: Investigational new drugs (2022)
Our results indicate a potential antineoplastic effect of galunisertib in HNSCC with intact TGF-ß signaling in combination with radiation.