Association of CD209 (DC-SIGN) rs735240 SNV with paucibacillary leprosy in the Brazilian population and its functional effects.

Giovanna Valle GermanoAndré Flores BragaRodrigo Mendes de CamargoPriscila Betoni BallalaiOhanna Cavalcanti BezerraFernanda Saloum de Neves MantaAndréa de Faria Fernandes BeloneCleverson Teixeira SoaresPranab Kumar DasMilton Ozório MoraesAna Carla Pereira LatiniVania Nieto Brito de Souza

Published in: Memorias do Instituto Oswaldo Cruz (2022)

These data suggest that rs735240 influences the immune response against M. leprae and clinical presentation of leprosy.

Keyphrases

immune response
dendritic cells
electronic health record
big data
inflammatory response