PET/NIR-II fluorescence imaging and image-guided surgery of glioblastoma using a folate receptor α-targeted dual-modal nanoprobe.
Xiaojing ShiPengfei XuCaiguang CaoZhen ChengZhenyu ZhangZhenhua HuPublished in: European journal of nuclear medicine and molecular imaging (2022)
Overall, our study demonstrates that the probes, <sup>64</sup>Cu-DOTA-FA-ICG and DOTA-FA-ICG, hold promise for preoperative PET examination and intraoperative NIR-II fluorescence image-guided surgery of GBM, respectively.
Keyphrases
- fluorescence imaging
- pet ct
- photodynamic therapy
- pet imaging
- minimally invasive
- coronary artery bypass
- positron emission tomography
- computed tomography
- patients undergoing
- surgical site infection
- single molecule
- big data
- living cells
- machine learning
- coronary artery disease
- small molecule
- deep learning
- cancer therapy
- artificial intelligence