Diffusion MRI Reversibility in Ischemic Stroke Following Thrombolysis: A Meta-Analysis.
Nikita LakomkinJonathan PanLaura SteinBrijesh MalkaniMandip DhamoonJ MoccoPublished in: Journal of neuroimaging : official journal of the American Society of Neuroimaging (2020)
These data suggest that early DWI signal may not represent the definitive DWI burden in recanalized populations. However, substantial heterogeneity exists regarding the rate of DWI reversal following recanalization. Additional studies are needed to elucidate the relationship among time to treatment, early reversal rates, and clinical outcomes. Physicians should use caution when basing clinical decisions on DWI lesion volumes, as these likely change to some degree with recanalization.
Keyphrases
- diffusion weighted imaging
- diffusion weighted
- contrast enhanced
- magnetic resonance imaging
- primary care
- middle cerebral artery
- pulmonary embolism
- endovascular treatment
- atrial fibrillation
- computed tomography
- magnetic resonance
- acute ischemic stroke
- risk factors
- electronic health record
- case control
- combination therapy