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Indoxyl Sulfate and p-Cresyl Sulfate Promote Vascular Calcification and Associate with Glucose Intolerance.

Britt OpdebeeckStuart MaudsleyAbdelkrim AzmiAnnelies De MaréWout De LegerBjorn MeijersAnja VerhulstPieter EvenepoelPatrick C D'HaeseEllen Neven
Published in: Journal of the American Society of Nephrology : JASN (2019)
In CKD, both IS and PCS directly promote vascular calcification via activation of inflammation and coagulation pathways and were strongly associated with impaired glucose homeostasis.
Keyphrases
  • chronic kidney disease
  • blood glucose
  • oxidative stress
  • type diabetes
  • skeletal muscle
  • weight loss