Osteoblasts are "educated" by crosstalk with metastatic breast cancer cells in the bone tumor microenvironment.

Alexus D KolbAlison B ShuppDimpi MukhopadhyayFrank C MariniKaren M Bussard

Published in: Breast cancer research : BCR (2019)

Our work reveals that there is a subpopulation of osteoblasts in the bone tumor microenvironment that demonstrate a functional role in retarding breast cancer cell growth.

Keyphrases

breast cancer cells
bone mineral density
soft tissue
squamous cell carcinoma
bone loss
bone regeneration
postmenopausal women
body composition