Aging Effect, Reproducibility, and Test-Retest Reliability of a New Cerebral Amyloid Angiopathy MRI Severity Marker-Cerebrovascular Reactivity to Visual Stimulation.
Suzanne E van DijkJessie LakNadieh DrenthAnne HafkemeijerSerge A R B RomboutsJeroen van der GrondSanneke van RoodenPublished in: Journal of magnetic resonance imaging : JMRI (2022)
Healthy aging is associated with decreased cerebrovascular reactivity, measured by changes in BOLD response to visual stimulation. The BOLD amplitude appears to be a robust measurement in healthy adults and presymptomatic D-CAA mutation carriers, but not in symptomatic D-CAA mutation carriers.