Familial adenomatosis polyposis-related desmoid tumours treated with low-dose chemotherapy: results from an international, multi-institutional, retrospective analysis.
Andrea NapolitanoSalvatore ProvenzanoChiara ColomboMarco VitellaroAntonella BrunelloGiuseppe BadalamentiMargherita NanniniToni IbrahimPeter HohenbergerSilvia GasperoniSpyridon GennatasRobin L JonesNadia HindiJavier Martin-BrotoMariella Spalato CerusoMarianna SillettaAngelo Paolo Dei TosAlessandro GronchiSilvia StacchiottiDaniele SantiniGiuseppe ToniniElena PalassiniBruno VincenziPublished in: ESMO open (2021)
This is the largest series on the activity of low-dose chemotherapy in patients with FAP-related DT. In this population, MTX+vinca alkaloids is an active combination, as already reported in patients with sporadic DT.