Familial adenomatosis polyposis-related desmoid tumours treated with low-dose chemotherapy: results from an international, multi-institutional, retrospective analysis.

Andrea NapolitanoSalvatore ProvenzanoChiara ColomboMarco VitellaroAntonella BrunelloGiuseppe BadalamentiMargherita NanniniToni IbrahimPeter HohenbergerSilvia GasperoniSpyridon GennatasRobin L JonesNadia HindiJavier Martin-BrotoMariella Spalato CerusoMarianna SillettaAngelo Paolo Dei TosAlessandro GronchiSilvia StacchiottiDaniele SantiniGiuseppe ToniniElena PalassiniBruno Vincenzi

Published in: ESMO open (2021)

This is the largest series on the activity of low-dose chemotherapy in patients with FAP-related DT. In this population, MTX+vinca alkaloids is an active combination, as already reported in patients with sporadic DT.

Keyphrases

low dose
high dose
locally advanced
early onset
late onset
squamous cell carcinoma
amyotrophic lateral sclerosis