Myeloablation Followed by Hematopoietic Stem Cell Transplantation and Long-Term Normalization of Systemic Sclerosis Molecular Signatures.
Nancy WareingXuan WangLynette Keyes-ElsteinEllen A GoldmuntzMarka A LyonsPeter McSweeneyDaniel E FurstRichard A NashLeslie J CroffordBeverly WelchAshley PinckneyMaureen D MayesKeith M SullivanShervin AssassiPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2024)
Paralleling the observed clinical benefit, HSCT leads to durable long-term normalization of the molecular signature in SSc, with completion of immune resetting to 54 months after HSCT.