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Genomic prediction with whole-genome sequence data in intensely selected pig lines.

Roger Ros-FreixedesMartin JohnssonAndrew WhalenChing-Yi ChenBruno D ValenteWilliam O HerringGregor GorjancJohn M Hickey
Published in: Genetics, selection, evolution : GSE (2022)
Our results showed that WGS has limited potential to improve the accuracy of genomic predictions compared to marker arrays in intensely selected pig lines. Thus, although we expect that larger improvements in accuracy from the use of WGS are possible with a combination of larger training sets and optimised pipelines for generating and analysing such datasets, the use of WGS in the current implementations of genomic prediction should be carefully evaluated against the cost of large-scale WGS data on a case-by-case basis.
Keyphrases
  • copy number
  • electronic health record
  • big data
  • gene expression
  • machine learning
  • rna seq