Associations of Stages of Objective Memory Impairment With Amyloid PET and Structural MRI: The A4 Study.
Ellen GroberRichard B LiptonReisa A SperlingKathryn V PappKeith A JohnsonDorene M RentzAmy E VeroffPaul S AisenAli EzzatiPublished in: Neurology (2022)
This study provides Class I evidence that, in normal older individuals, higher stages of memory impairment assessed with FCSRT were associated with higher amyloid imaging burden and lower volume of hippocampus, entorhinal cortex, and inferior temporal lobes.