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Systemic vascular photobiomodulation accelerates the recovery of motor activity in rats following spinal cord injury.

Daysi da C TobelemLucas AndreoTamiris SilvaTainá C S MalavazziAndreia MartinelliAnna Carolina Ratto Tempestine HorlianaKristianne P S FernandesSandra K BussadoriRaquel Agnelli Mesquita-Ferrari
Published in: Lasers in surgery and medicine (2023)
The present results showed that VPBM was capable of modulating morphological and functional recovery following SCI, especially when administered early. The positive effects on functional recovery were demonstrated by the BBB index; the reestablishment of the structure of the muscle and nerve tissue was demonstrated by the preservation of CSA and diameter of muscle fiber and reduction in the area of the injury (cavity size) respectively. Thus, noninvasive VPBM may be an important component of treatment for spinal cord injuries.
Keyphrases
  • spinal cord injury
  • spinal cord
  • skeletal muscle
  • neuropathic pain
  • blood brain barrier
  • optic nerve