Quantitative characterization of T-cell repertoire and biomarkers in kidney transplant rejection.

Houda AlachkarMartin MutongaTaigo KatoSowjanya KalluriYoichi KakutaMotohide UemuraRyoichi ImamuraNorio NonomuraVikas VujjiniSami AlasfarHamid RabbYusuke NakamuraNada Alachkar

Published in: BMC nephrology (2016)

Our study provides a potential utilization of TCR clone kinetics analysis in the diagnosis of TCMR. This approach may allow for the identification of the expanded T-cell clones associated with the rejection and lead to potential noninvasive diagnosis and targeted therapies of TCMR.

Keyphrases

human health
regulatory t cells
risk assessment
mass spectrometry
data analysis