Login / Signup

Trajectories of functional decline in older adults with neuropsychiatric and cardiovascular multimorbidity: A Swedish cohort study.

Davide Liborio VetranoDebora RizzutoAmaia Calderón-LarrañagaGraziano OnderAnna-Karin WelmerRoberto BernabeiAlessandra MarengoniLaura Fratiglioni
Published in: PLoS medicine (2018)
In older adults, different patterns of CV and NP morbidity lead to different trajectories of functional decline over time, a finding that explains part of the heterogeneity observed in older adults' functionality. NP diseases, alone or in association, are prevalent and major determinants of functional decline, whereas isolated CV multimorbidity is associated only with declines in mobility.
Keyphrases
  • physical activity
  • depressive symptoms
  • single cell