SIRT-3 Modulation by Resveratrol Improves Mitochondrial Oxidative Phosphorylation in Diabetic Heart through Deacetylation of TFAM.

Pankaj K BagulParmeshwar B KatareParamesha BuggaAmit K DindaSanjay K Banerjee

Published in: Cells (2018)

Together our data shows that resveratrol activates SIRT-3, regulates the acetylation status of TFAM and preserves the mitochondrial function along with cellular size in diabetic rat heart.

Keyphrases

oxidative stress
type diabetes
heart failure
wound healing
ischemia reperfusion injury
atrial fibrillation
electronic health record
big data
histone deacetylase