Ir-Catalyzed Distal Branch-Selective Hydroarylation of Unactivated Internal Alkenes with Benzanilides via C-H Activation along with Consecutive Isomerization.

We herein report a synergistic strategy of C-H activation and consecutive isomerization catalyzed by an Ir catalyst to selectively obtain branched isomers as C-H alkylated products of benzanilide derivatives. A well-tuned ligand and a directing group are crucial to achieve this selectivity. The scope of this reaction is demonstrated by the use of a variety of substituents and complex molecules.