The Deep Learning Framework iCanTCR Enables Early Cancer Detection Using the T-cell Receptor Repertoire in Peripheral Blood.
Yideng CaiMeng LuoWenyi YangChang XuPingping WangGuangfu XueXiyun JinRui ChengJinhao QueWenyang ZhouBoran PangShouping XuYu LiQinghua JiangZhao-Chun XuPublished in: Cancer research (2024)
Development of a deep learning-based method for multicancer detection using the TCR repertoire in the peripheral blood establishes the potential of evaluating circulating immune signals for noninvasive early cancer detection.
Keyphrases
- peripheral blood
- deep learning
- papillary thyroid
- loop mediated isothermal amplification
- real time pcr
- label free
- squamous cell
- artificial intelligence
- convolutional neural network
- squamous cell carcinoma
- lymph node metastasis
- immune response
- climate change
- risk assessment
- childhood cancer
- sensitive detection
- quantum dots