Identification of miR-379/miR-656 (C14MC) cluster downregulation and associated epigenetic and transcription regulatory mechanism in oligodendrogliomas.

Anupam KumarSubhashree NayakPankaj PathakSuvendu PurkaitPrit Benny MalgulawarMehar Chand SharmaVaishali SuriArijit MukhopadhyayAshish SuriChitra Sarkar

Published in: Journal of neuro-oncology (2018)

Our work demonstrates tumor-suppressive role of C14MC and its role in pathogenesis of ODGs and therefore could be relevant for the development of new therapeutic strategies.

Keyphrases

cell proliferation
long non coding rna
long noncoding rna
transcription factor
dna methylation
gene expression
signaling pathway
bioinformatics analysis