Simultaneous administration of cocaine and caffeine dysregulates HCN and T-type channels.
María Celeste Rivero-EchetoPaula P PerissinottiCarlota González-InchauspeLucila KargiemanVerónica BisagnoFrancisco José UrbanoPublished in: Psychopharmacology (2020)
Our results suggest that deleterious consequences of stimulants cocaine and caffeine combination on the thalamocortical physiology as a whole might be related to potential neurotoxic effects of soaring intracellular [Ca2+].